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In a surprising move, the U.S. Food and Drug Administration (FDA) has opted not to approve a needle-free alternative to the EpiPen for emergency treatment of severe allergic reactions.

Approval of the Neffy nasal spray was widely anticipated. An FDA advisory panel voted to recommend approval of the drug for children and adults in May. While the FDA is not obligated to follow the advice of...

Maybe you can't weed your garden without sneezing. Perhaps your eyes start watering when you clean your home. Did your skin begin itching last night during dinner?

You may have an allergy, but you're not alone. More than 50 million adults and children in the United States have a bad reaction to pollen, dust, mold, pet dander and other common allergens, according to the

  • Meredith Morckel HealthDay Reporter
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  • May 22, 2023
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  • Full Page
  • Outside advisors for the U.S. Food and Drug Administration voted Thursday to recommend approval of Neffy, the first epinephrine nasal spray for severe allergic reactions.

    Although most of the Pulmonary-Allergy Drugs Advisory Committee members supported the spray for adults (16:6) and children (17:5), key questions linger about whether more data is needed from its maker, ARS Pharmaceutical...

    Having a latex allergy is no fun, but it can be a real challenge for health professionals who have to work with a wide variety of medical equipment that can contain the allergen.

    Latex allergy can trigger a range of symptoms, from itchy hives and rashes to life-threatening anaphylaxis. While StatPearls estimates that it

  • Ann Schreiber HealthDay Reporter
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  • May 9, 2023
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  • Full Page
  • So, you ate a banana. You've eaten bananas countless times in the past. But this time, your tongue and lips are itching and your lip is a bit puffy.

    If this happens to you, you are likely experiencing food allergy symptoms. You may have just joined the ranks of 32 million Americans who deal with food all...

    Sesame isn't declared on more than half of food products that contain it, which could put some people at risk for an allergic reaction, researchers warn.

    A serious allergic reaction (anaphylaxis) can be deadly.

    By 2023, sesame will have to be listed on labels of food products sold in the ...

    Some kids might be able to get over their peanut allergy if they start immunotherapy while they're still toddlers, a major new clinical trial reports.

    In the trial, a group of 1- to 3-year-olds with severe peanut allergies were safely fed gradually increasing daily doses...

    Pfizer Inc. has agreed to pay $345 million in a proposed settlement to resolve lawsuits over steep EpiPen price increases.

    EpiPens are auto-injectable devices that deliver the drug epinephrine for emergency treatment of a life-threatening allergic reaction called anaphylaxis.

    In 2016, a number of class-action lawsuits were filed against Pfizer and its subsidiaries Meridian Medical T...

    A new clinical trial will investigate whether people who are highly allergic or have what's known as a mast cell disorder are at higher risk for a sudden allergic reaction to the Moderna or Pfizer COVID-19 vaccines.

    "The public understandably has been concerned about reports of rare, severe allergic reactions to the Moderna and Pfizer-BioNTech COVID-19 vaccines," said Dr. Anthony Fauci, d...

    Worried or wondering about COVID-19 vaccines?

    Many Americans are, so experts at Penn State Health are offering some reassuring insight.

    "People are approaching this vaccine with more hesitation because it was approved quickly, but that really just speaks to how far we have come in vaccinology," said Dr. Mohammad Ali, an infectious disease physician at Penn State Health Holy Spirit M...

    Only a tiny fraction of the nearly 14 million COVID-19 vaccine doses administered in the first month of vaccinations produced any sort of adverse event, U.S. health officials report.

    There were 6,994 reports of adverse events following a shot of the COVID vaccine between Dec. 14, 2020 and Jan. 13, 2021, amounting to about half a percent of the 13.8 million doses doled out during that peri...

    Black American children have higher rates of shellfish and fish allergies than white children, a new study finds.

    The research confirms the important role that race plays in children's food allergies, the study authors said.

    "Food allergy is a common condition in the U.S., and we know from our previous research that there are important differences between African American and white ...

    A task force of allergists and immunologists recommends those administering the COVID-19 vaccine ask patients some key questions beforehand.

    While reactions to vaccines are extremely rare, the American College of Allergy, Asthma and Immunology (ACAAI) said anyone being vaccinated should be asked if they have a history of a severe allergic reaction ...

    Cases of anaphylactic shock caused by COVID-19 vaccines are very rare, based on numbers from the first week and a half of vaccinations in the United States, federal public health officials said Wednesday.

    There have been 21 cases of anaphylaxis out of nearly 1.9 million doses of the Pfizer-BioNTech vaccine administered in the very first days of the national COVID-19 vaccination program, s...

    In very rare cases, some people have had severe allergic reactions after receiving the new COVID-19 vaccines, leading the American College of Allergy, Asthma, and Immunology (ACAAI) to issue updated guidance for Americans with allergies.

    The U.S. Food and Drug Administration has given emergency use authorization to COVID-19 vaccines from Pfizer-BioNTech and Moderna.

    The ACAAI's COVI...

    The sting of fire ants can be painful and even deadly -- and the threat rises during fall across the southeastern United States.

    At this time of year, fire ants move to warm surfaces such as concrete slabs or asphalt roads, according to the American College of Allergy, Asthma and Immunology (ACAAI), which urges people to take precautions.

    A child can be stung walking through...

    Parents of kids with food allergies probably won't be surprised to hear that Halloween is an especially risky time for their youngsters.

    A new study found that serious allergic reactions (anaphylaxis) triggered by peanuts jumped 85% when kids were trick or treating. Serious reactions triggered by an unknown tree nut or peanut exposure rose by 70% on Halloween compared to the ...

    Pills used to treat blood cancers may potentially prevent life-threatening allergic reactions, early research hints.

    That could spell good news for people with severe food and drug allergies.

    In lab experiments, researchers found that a group of medications -- called BTK inhibitors -- can put the brakes on the process that triggers life-threatening allergic reactions known...

    Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food and Drug Administration warns.

    Problems may occur in EpiPen 0.3 mg and EpiPen Jr 0.15 mg auto-injectors and authorized generic versions due to device malfunctions and user errors, according to the agency.

    The devices may...

    Giving antihistamines to a child suffering a potentially fatal allergic reaction may do more harm than good if it causes a delay in emergency treatment, a new study warns.

    Researchers reviewed the medical records of young patients, aged 8 months to 20 years, who were admitted to a pediatric intensive care unit for treatment of anaphylaxis between July 2015 and January 2019.

    ...

    The idea behind immunotherapy for peanut allergy is appealing in its simplicity: Ask a patient to eat tiny amounts of peanut every day, and over time their immune system will become desensitized to it.

    Unfortunately, this cure might be doing more harm than the allergy itself, a new evidence review suggests.

    People who undergo immunotherapy for their peanut allergies wind up with...

    You might be surprised to learn that food allergies can start in adulthood and involve a food you've eaten without a problem for your entire life.

    For adults as well as kids, the top -- but not the only -- food culprits are eggs, milk, peanuts, tree nuts, fish and shellfish, wheat and soy, according to the American College of Allergy, Asthma and Immunology.

    Just as with chi...

    Allergies to vaccines are extremely rare and even when they do occur, allergists can safely administer vaccines, Canadian experts report.

    Immunoglobulin E (IgE) allergies that cause hives, swelling, wheezing or anaphylaxis occur in only 1 of 760,000 vaccinations.

    Such a reaction typically starts within minutes of a shot, is unlikely to occur after 60 minutes, and is highly u...

    Allergic reactions to peanuts can be incredibly dangerous, causing the throat to close, the chest to tighten, and throw a person into life-threatening anaphylactic shock.

    But researchers now believe they've found a way to head off that immune reaction by blocking the antibodies that cause it.

    There appear to be two specific allergens in peanut proteins that produce the most ...