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Health News Results - 341

U.S. approval of the Alzheimer's drug Aduhelm is already mired in controversy. Now a new study finds that most Alzheimer's patients could not have taken part in clinical trials that led to the green light.

In June, the U.S. Food and Drug Administration gave accelerated approval to Aduhelm (aducanumab) for treating patients with mild cognitive impairment or mild dementia from Alzheimer's d...

As the COVID-19 pandemic grinds on and stress on families mounts, more kids are falling victim to accidental poisoning.

Experts attribute the surge to disrupted sleep patterns, work schedules and parenting routines.

"I think what's happening is, parents are challenged with a couple of things," said Helen Arbogast, manager of the Injury Prevention Program at Children's Hospital Los ...

The prescribing, dispensing and use of ivermectin to prevent or treat COVID-19 outside of clinical trials must end immediately, the American Medical Association, American Pharmacists Association and American Society of Health-System Pharmacists say.

The drug has U.S. Food and Drug Administration approval to treat people with infections caused by internal and external parasites, but is not...

As doctors around the world come up against severe cases of COVID-19, some positive news has emerged: New research shows the rheumatoid arthritis drug baricitinib may help reduce hospitalized COVID patients' risk of death.

Current standard-of-care medications aren't enough, said study co-author Dr. E. Wesley Ely, a professor of medicine at Vanderbilt University Medical Center in Nashville...

A four-in-one pill containing "ultra-low doses" of different medications can provide better blood pressure control than standard drug treatment, a new clinical trial from Australia shows.

About 80% of people given the "quadpill" achieved a healthy blood pressure of 140/90 within three months and continuing out to a year, compared to 60% of people who started on a single medication and add...

Leaky sewer pipes are to blame for large amounts of human medicines getting into rivers, lakes and other bodies of water, a new study reveals.

Researchers found that tens of thousands of doses of drugs get into Chesapeake Bay in Maryland every year due to seeping sewer pipes.

"Pharmaceuticals enter freshwaters through multiple pathways, including effluent from wastewater treatment a...

The anesthesia drug ketamine and a related medicine called esketamine appear to be safe for tough-to-treat depression, researchers report.

A number of studies have suggested that low doses of ketamine, which is also abused as a club drug under monikers that include "K" and "Special K," provide rapid antidepressant effects, typically improving mood within 24 hours to seven days.

Sim...

Five years after the U.S. Centers for Disease Control and Prevention retooled a guideline for prescribing opioid painkillers, research suggests the change is paying off.

With the United States in the grip of an opioid overdose epidemic, the CDC released an evidence-based guideline in 2016 to help doctors treat patients' pain while balancing the risks and benefits of prescription opioids....

When the antiretroviral regimen known as pre-exposure prophylaxis, or PrEP, was launched nearly a decade ago, patients were suddenly able to achieve near-complete protection against contracting HIV by taking just one pill a day.

But there's a big hitch: Not everyone is equally diligent about sticking to that once-a-day daily pill regimen, and when doses are missed PrEP's protective shield...

The two HIV prevention drugs available in the United States are equally safe and effective, and the biggest difference between them is price, a new study contends.

However, a sizable minority of patients have switched from the older and cheaper "preexposure prophylaxis" (PrEP) formulation to the newer and much pricier one. In many cases that switch might not have been warranted, the resea...

Since 2008, anti-seizure drugs have carried a warning that they may increase users' suicide risk. But a new analysis finds no evidence of such a risk with newer medications.

Researchers found that five medications approved since 2008 showed no link to suicide risk among patients who participated in clinical trials of the drugs.

The findings, they said, argue against the "blanket" wa...

Could a drug used to treat amyotrophic lateral sclerosis (ALS) help people with mild Alzheimer's disease?

The results of a small new study suggest the strategy could work.

Riluzole has been used for more than 20 years to slow the progression of ALS, commonly called Lou Gehrig's disease. This phase 2 study found that the drug slowed brain metabolic decline and had a positive effect o...

An outside advisor to the U.S. Food and Drug Administration's review of the controversial Alzheimer's drug Aduhelm is now speaking out, arguing that the approval was based on dodgy science and involved questionable collaboration between regulators and the drug's maker.

"I'm not surprised at the controversy because I think it's a horrible decision. I think the FDA got it wrong," said Dr. G...

Two long used types of blood pressure drugs are equally effective, but the less popular one seems to have fewer side effects, according to a large "real-world" study.

The two classes of medication are both recommended as "first-line" treatments for high blood pressure: angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs).

ACE inhibitors have been a...

Accidental exposure to fentanyl pain patches is putting children's lives at risk, the U.S. Food and Drug Administration warns.

Fentanyl is a powerful opioid pain reliever; so powerful that fentanyl patches are typically only prescribed to patients who require round-the-clock, long-term pain relief, such as cancer patients. They're generally replaced every three days.

Kids can overdo...

The controversial new Alzheimer's drug Aduhelm is creating something of a civil war in medicine, as health networks, hospitals, insurers and individual doctors weigh impending discussions with patients about whether they should take the medication.

Many doctors believe the U.S. Food and Drug Administration "moved the goalposts" to approve Aduhelm (aducanumab) in early June, and they aren'...

A drug that eases hallucinations in people with Parkinson's disease may be able to do the same for those with dementia, a new clinical trial finds.

The medication, called Nuplazid (pimavanserin), is already approved in the United States for treating hallucinations and delusions related to Parkinson's.

The new study, published July 22 in the New England Journal of Medicine, ...

Prescriptions for U.S. children fell by about one-quarter during the COVID-19 pandemic, with prescriptions for antibiotics alone plunging by more than 50%, a new study finds.

The findings are a "national picture of prescription drug dispensing to children before and during the pandemic. It will be important to monitor whether the reductions we demonstrate are temporary or sustained," said...

Although tens of millions of Americans turn to muscle relaxants for lower back pain relief, a new Australian review finds little evidence that such drugs actually work.

That's the conclusion of a deep-dive into 31 prior investigations, which collectively enlisted more than 6,500 lower back pain patients. Enrolled patients had been treating lower back pain with a wide range of 18 different...

The U.S. Food and Drug Administration on Thursday issued new prescribing rules for the controversial Alzheimer's medication Aduhelm that will likely limit its use.

When first approved a month ago, the FDA said Biogen's monthly IV drug was for all Alzheimer's patients. The agency now says the drug is appropriate for patients with early or mild Alzheimer's but that it has not been studied i...

Can Costco beat Medicare Part D when it comes to prescription drug prices?

Apparently so, claims a new study that found that roughly half of generic medications were cheaper when purchased from the discount retailer than from the government program.

The researchers compared the prices paid by Medicare Part D plans (including patient out-of-pocket payments) for 184 generic prescripti...

TUESDAY, June 29, 2021 (HealthDay News) --Walmart said Tuesday that it will start selling its own private brand of insulin at much lower prices than competing products.

Insulin prices have skyrocketed in recent years, making it unaffordable for some Americans with diabetes, according to CBS News.

"We know many people with diabetes struggle to manage the financial burden of ...

You have type 2 diabetes, and you are already taking an old standby drug, metformin. But you still need help controlling your blood sugar levels. Which medication would be the best?

New research pitted several diabetes drugs against each other and came up with an answer: The diabetes drugs Lantus and Victoza were better at controlling blood sugar over time than Amaryl or Januvia.

"W...

Older adults who use certain blood pressure drugs may retain more of their memory skills as they age, a new study suggests.

Researchers found the benefit among older people taking medications that are allowed past the "blood-brain barrier," which is a border of specialized cells that prevents toxic substances from crossing into the brain.

Those drugs include certain ACE inhibitors a...

A new research review offers good news for migraine sufferers: There are more pain-relieving options than ever.

In an analysis of over 100 published studies, researchers found that several drug classes showed good evidence they ease the pain of a migraine-in-progress.

Some of those medications have only become available in the past few years, opening up new options for migraine suff...

Certain cholesterol-lowering drugs might speed dementia in some older adults whose memories are starting to fail, a small, preliminary study suggests.

The researchers found that of 300 older adults with mildly impaired thinking and memory, those using "lipophilic" statins were more likely to develop dementia over the next eight years.

Lipophilic statins include such widely used medi...

Living longer often means living with multiple health problems and numerous medications to manage them. Understandably, many doctors and their patients wonder if any of these drugs can be discontinued safely.

A new study from Italy suggests statins should not be culled from the list.

Among more than 29,000 adults 65 and older, those who stopped taking these cholesterol-lowering drug...

ADHD medications might help lessen the risk of suicide in children with serious behavioral issues, a new study suggests.

Researchers found that medications like Ritalin and Adderall, commonly prescribed for attention-deficit/hyperactivity disorder (ADHD), were linked to a lower risk of suicidal behavior among 9- and 10-year-olds with substantial "externalizing" symptoms.

That includ...

The U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defending its reputation and its science.

Aduhelm (aducanumab) treats Alzheimer's by clearing out amyloid beta, a sticky protein known to form plaques in the brains of early-stage patients.

It is the first approved...

The first drug ever shown to slow the progression of Alzheimer's disease could be approved by the U.S. Food and Drug Administration on Monday, but experts say that approval will be surrounded by controversy.

In clinical trials, aducanumab showed a 22% reduction in the development of thinking and memory problems associated with Alzheimer's disease, according to a statement from the Alzheim...

A twice-daily pill can dramatically reduce the risk of breast cancer recurrence in women who are genetically prone to the disease, researchers report.

The pill - olaparib (Lynparza) - works by blocking a natural enzyme called PARP that normally fixes DNA damage in healthy cells, but in these women actually promotes the growth of cancerous cells.

Early high-risk breast cancer patient...

The U.S. government and nonprofits are replacing drug companies as the main drivers of Alzheimer's disease research, two new studies show.

The findings are from an analysis of national data by Jeffrey Cummings, a research professor at the University of Nevada, Las Vegas School of Integrated Health Sciences.

In one study, his team found that the number of Alzheimer's clinical trials ...

Use of the opioid overdose reversing medication naloxone has declined in the United States during the COVID-19 pandemic, researchers found.

The study authors said their findings suggest that people with opioid misuse disorders may be facing a dangerous decrease in access to naloxone.

"In March of 2020, we saw a sharp reduction in the average number of individuals filling naloxone pr...

Not taking prescribed medications can lead to relapse, hospitalization and increased risk of suicide for people with bipolar disorder, yet many who have this condition do not take their medicines as prescribed.

A new study examines why this happens, finding six key factors that stop people who have bipolar disorder from taking their medications.

The reasons include unpleasant side...

You want to keep Fido or Fluffy safe, so when they need medication, it's important to ask questions and guard against dosing errors, the U.S. Food and Drug Administration says.

"A number of the medication errors that occur in the treatment of people are the same as those we are seeing in the treatment of animals," said Linda Kim-Jung. She's a safety reviewer in the Center for Veterinary M...

An experimental injectable drug appears more versatile than existing medications in treating people with different forms of severe, hard-to-control asthma, clinical trial results show.

There are many different types of asthma brought on by many different triggers, and a number of monoclonal antibody medications -- called "biologics" -- have been crafted to target distinct asthma triggers....

An estimated 9 million Americans turn to prescription pills when they can't sleep, but a new study of middle-aged women finds taking the drugs for a year or longer may do little good.

Comparing a group of about 200 women who were medicated for sleep problems with over 400 women who had sleeping problems but did not take medication, researchers from Brigham and Women's Hospital in Boston f...

Serious cases of "long-haul COVID-19" are rare in patients who were not hospitalized after their infection, but these patients still report more doctor or health care visits after recovery,. Danish researchers report.

The new six-month study found that COVID patients who were not hospitalized had small increased risks of blood clots and breathing difficulties. They were also more likely t...

Nearly one in five Americans with high blood pressure use medications that can cause blood pressure to spike, a preliminary study shows.

The researchers said the findings are concerning, given how many people have difficulty controlling their high blood pressure.

"A large number of Americans are not meeting their blood pressure goals," said lead researcher Dr. John Vitarello, an int...

When prescription drug "list" prices go up, patients often take a hit in the wallet, a new study shows.

Researchers found that while some people are buffered against drug price hikes by their health insurance plan, many are not.

Those in plans that require co-insurance or a deductible for prescriptions typically watch their out-of-pocket expenses rise, according to the study.

The weight-loss drug Saxenda can keep extra pounds off -- but combining it with exercise brings a bigger payoff, a new clinical trial finds.

The study found that some longstanding advice is valid: Prescription weight-loss drugs work best when used along with -- and not in place of -- lifestyle changes.

Saxenda (liraglutide) is a prescription drug approved in the United States for sp...

Parents of preschoolers with attention deficit hyperactivity disorder (ADHD) may be advised to give their child medication to help them concentrate, sit still and/or control impulsive behaviors.

A new study comparing two classes of medications might help them arrive at a decision.

While stimulants are often first in line, the research shows that another class of ADHD drugs known as ...

One-third of neighborhoods in the 30 largest U.S. cities are "pharmacy deserts," and this is much more common in Black and Hispanic communities, a new study finds.

What's a 'pharmacy desert'? In general, in a neighborhood where most residents have cars, the study labeled it a pharmacy desert if the average distance to the nearest pharmacy was 1 mile or more. That distance was reduced to ...

Many people take fish oil to protect their heart, but a new study suggests that prescription versions may raise the risk of a common heart rhythm disorder.

At issue are prescription-strength omega-3 fatty acids, which are naturally found in fish oil. The medications are often prescribed to people with very high triglycerides, a type of blood fat linked to increased risk of he...

Getting a prescription for an opioid painkiller from your dentist could put you or your family at risk for an overdose, a new study warns.

The finding is based on an analysis of data from 8.5 million Americans who had teeth pulled or 119 other types of dental work between 2011 and 2018. All had Medicaid or private dental insurance.

"Our paper shows that when patients fill dental opi...

The Biden administration has eased guidelines for prescribing a crucial addiction treatment drug, just as a new study reveals one in five U.S. pharmacies refuses to dispense the medication, called buprenorphine.

"Buprenorphine is a vital, lifesaving medication for people with opioid use disorder, but improving access has been a problem for a variety of reasons," said the study's senior au...

A breakthrough psoriasis drug is better at treating the itchy and painful skin disease than medicines already on the market, according to results from two clinical trials.

There was a "night and day difference" in the results from bimekizumab compared against two established psoriasis drugs, secukinumab (Cosentyx) and adalimumab (Humira), said Dr. Mark Lebwohl, a co-researcher in one of t...

It may not be a good idea to take a daily low-dose aspirin if you're also taking a widely used class of blood thinners called direct oral anticoagulants (DOACs), researchers caution.

DOACs include drugs such as Eliquis (apixaban), Pradaxa (dabigatran), Lixiana (edoxaban) and Xarelto (rivaroxaban). They're used to help prevent strokes from atrial fibrillation or for the treatment of what's...

Black people experience more severe courses of multiple sclerosis (MS), and now new research suggests that drugs commonly used to treat this disease may not work as well or for as long in these folks.

"I was amazed," said study researcher Dr. Gregg Silverman, a professor of medicine at NYU Langone Health in New York City. In a study of two drugs, "there was a dramatic and significant diff...

The magic ingredient in "magic mushrooms" may be at least as effective as standard medication for depression, an early clinical trial suggests.

The study of 59 patients with major depression tested the antidepressant escitalopram (Lexapro) against psilocybin, which is the psychedelic substance in hallucinogenic mushrooms.

Over six weeks, it appeared that just two doses of psilocybi...