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For men with advanced prostate cancer, a new hormone therapy pill works better than standard injections -- and carries a much lower risk of heart attack or stroke, a clinical trial has found.

The drug, called relugolix, is not yet approved by the U.S. Food and Drug Administration. If it gets the green light, however, it would be "game-changing," said Dr. Neal Shore, lead researcher on...

Prostate cancer screening guidelines have been evolving for more than a decade, but new research suggests that recommendations against routine prostate cancer testing may have come at a steep price -- more men getting diagnosed with advanced prostate cancers.

The study found that rates of advanced prostate cancers rose by about 5% per year through 2016.

There was some ...

The coronavirus pandemic has many people putting off medical appointments, but if you have possible cancer symptoms, don't delay.

A small lump in a breast, blood in your stool or an odd-looking mole, for example, should not be ignored, according to experts at Cedars-Sinai Health System in Los Angeles.

"We're seeing a concerning trend that some cancer diagnoses are being de...

New treatments for melanoma have dramatically reduced deaths from this often fatal skin cancer.

Leaders of a new study report that the death rate from aggressive melanoma that spread to other organs plummeted 18% between 2013 and 2016, after jumping 7.5% between 1986 and 2013. The figures apply to white Americans, the group that accounts for nearly all cases of melanoma in th...

People with a history of certain cancers have more than double the risk for the heart rhythm disorder atrial fibrillation, a new study says.

A-fib is a common disorder that can lead to palpitations, dizziness and fatigue. Untreated, it can cause blood clots, stroke and heart failure, and people with a-fib have five times the risk of stroke than other people.

"When we looked ...

Exercise benefits prostate cancer patients who undergo hormone-reducing therapy, a small study suggests.

The treatment -- called androgen suppression therapy or androgen deprivation therapy (ADT) -- uses drugs or surgery to reduce the level of androgen hormones, which prostate cancer cells typically require to multiply.

"The problem is ADT has several side effects, including...

A test that can detect the genetic "fingerprint" of prostate cancer in blood could improve diagnosis, monitoring and treatment of the disease, researchers say.

The test checks for prostate cancer DNA in blood in order to provide the earliest evidence that prostate cancer is active.

This could help doctors monitor tumor behavior, determine if cancer has spread ("metastasized"...

Here's more motivation for men to shed pounds if they're overweight: It could lower their risk for advanced prostate cancer.

Researchers analyzed data from 15 studies that included a total of nearly 831,000 men, including nearly 52,000 who'd been diagnosed with prostate cancer.

Having a BMI (body mass index -- an estimate of body fat based on height and weight) above the ran...

Adding MRI to a standard tissue biopsy appears to enhance the accuracy of a prostate cancer diagnosis, new research finds.

The study, led by researchers at the U.S. National Cancer Institute (NCI), found that combining the two methods cut the rate of "underdiagnosis" by more than half, compared to use of either MRI or biopsy alone.

"With the addition of MRI-targeted biopsy t...

Every day, millions of Americans pop a fish oil supplement -- rich in healthy omega-3 fatty acids -- in hopes it'll improve their health.

A big new data review suggests they may be half right: The supplements may slightly reduce a person's risk of heart disease, but they won't ward off cancers.

In fact, men who took the supplements actually had a slight uptick in their ris...

Drugs that many men with prostate cancer might already be taking -- cholesterol-lowering statins -- may help extend their survival if they have a "high-risk" form of the disease, new research suggests.

High-risk patients include men with high blood levels of prostate specific antigen (PSA) and a "Gleason score" of 8 or more. Gleason scores are a calculation used to gauge prognosis in...

High levels of the sex hormone testosterone may trigger different health problems in men and women, a new study reveals.

In women, testosterone may increase the risk for type 2 diabetes, while in men it lowers that risk. But high levels of testosterone increase the risk for breast and endometrial cancer in women and prostate cancer in men, the researchers reported.

"Our fi...

Survival rates are similar for black and white prostate cancer patients who are treated in an equal-access health system, researchers say.

In the general U.S. population, black men are more likely than white men to be diagnosed with advanced prostate cancer, and more than twice as likely to die from the disease.

In a new study, researchers assessed whether this racial dispar...

Eating a diet high in vegetables and fruits does not slow or cure prostate cancer, according to a new study.

U.S. guidelines say prostate cancer patients might benefit from eating a vegetable-rich diet.

This study included 478 men, ages 50 to 80. All had been diagnosed with early-stage prostate cancer and were under active surveillance, meaning they were closely monitored an...

In another step toward using artificial intelligence in medicine, a new study shows that computers can be trained to match human experts in judging the severity of prostate tumors.

Researchers found that their artificial intelligence system was "near perfect" in determining whether prostate tissue contained cancer cells. And it was on par with 23 "world-leading" pathologists in judgin...

Nearly two decades after terrorists attacked New York's World Trade Center, certain cancers are striking police and recovery workers who saved lives, recovered bodies and cleaned up the wreckage.

This particular group of responders appears to have an increased risk of developing thyroid cancer, leukemia and prostate cancer, as well as a slightly elevated overall risk of cancer, resear...

A 29% drop in U.S. cancer deaths between 1991 and 2017 was driven by declines in deaths from four major cancers -- lung, colon, breast and prostate, according to the latest American Cancer Society (ACS) annual report.

Cancer deaths in the United States fell 2.2% between 2016 and 2017, the largest-ever single-year decrease.

That record drop was spurred by a rapid decl...

Here's some worrisome news for folks who manage to survive a heart attack: New research suggests they might be far more vulnerable to developing cancer down the road.

People who suffered a heart health scare -- a heart attack, heart failure or a dangerously erratic heart rhythm -- had a more than sevenfold increased risk for subsequently developing cancer, compared to those with healt...

A drug that targets faulty gene repair may buy more time for some men with advanced prostate cancer, a new clinical trial finds.

Experts called the study "landmark," because it zeroed in on men with particular gene mutations that can be targeted with newer drug therapies. It's an approach that is already used in treating breast, ovarian and lung cancers.

Specifically, the tr...

In the largest investigation of its kind, researchers conclude that subjecting prostate cancer patients to radiation therapy immediately after surgery doesn't give them an advantage in staying cancer-free.

The finding stems from a review of four studies that together tracked outcomes for more than 3,500 prostate cancer patients from multiple countries.

If the findings help c...

Could male infertility contribute to a higher risk for prostate cancer?

Yes, according to new Swedish research that suggests that men who become fathers through assisted reproduction treatments may be more likely to develop prostate cancer in midlife.

The conclusion follows a review of data collected by a Swedish national registry between 1994 and 2014. In all, 1 million chi...

If you are a senior who is poor or from a minority group, the chances may be higher that you could receive a cancer diagnosis in the emergency room, a new study suggests.

Cancer is typically diagnosed by a specialist, but 20% to 50% of cancers are only caught during an ER visit, researchers said.

"Emergency room detection of cancer provides a window to understanding ...

Running contrary to current guidelines, new research suggests that use of hormone-suppressing treatment over the long term may not help some men battling recurrent prostate cancer, and may even cause harm.

In fact, the study found that long-term hormone therapy was tied to a raised risk of death from other causes for some patients who received it.

Blood levels of prostate-sp...

In what might be a major breakthrough, researchers report that high doses of radiation dramatically prolonged survival in men battling an advanced and aggressive form of prostate cancer.

This particular type of cancer occurs when tumors resurface and spread to a number of areas beyond the prostate among patients who were in remission following radiation, surgery or chemotherapy. Gene...

Prostate cancer is the second most common cancer in American men, so it's important to know the risk factors and warning signs, an expert says.

The American Cancer Society estimates there will be nearly 175,000 new prostate cancer cases in the United States this year and over 31,000 deaths. One in nine men will be diagnosed with prostate cancer in their lifetime.

"The diseas...

Since the turn of the century, American obesity rates have skyrocketed. And now a new study indicates that as the nation's waistlines expand, cancers long linked to obesity are striking the middle-aged more than ever before.

The finding follows a review of data on more than 6 million white, black and Hispanic cancer patients diagnosed between 2000 and 2016.

The upshot: Acros...

When men have both advanced prostate cancer and heart disease, treatment may pose a dilemma: Newer hormonal therapies that can slow the cancer down might also be risky for their hearts, a new study finds.

Once prostate cancer spreads beyond the gland, one of the mainstays of treatment is hormone therapy. The aim is to prevent androgens ("male" hormones such as testosterone) from feedi...

The oldest Americans have higher cancer screening rates but lower cancer survival rates than younger seniors, a new report shows.

Those 85 and older -- a group dubbed the oldest old -- are also less likely to have cancer surgery than their counterparts between 65 and 84 years of age.

Adults aged 85 and up are the fastest-growing age group in the United States, yet relatively...

Many men with prostate cancer rely on common testosterone-blocking drugs as a part of their treatment. But those so-called antiandrogens also might put them at risk for a deadly heart condition, according to new research.

In a study published Monday in the American Heart Association journal Circulation, researchers looked at how several testosterone-blocking drugs affect the h...

Soon after a man is diagnosed with prostate cancer, drugs that lower levels of testosterone are often offered as treatment, since testosterone fuels the cancer's growth.

But a major new study suggests that this approach might have an unwanted side effect: Higher odds for Alzheimer's disease and other dementias.

"Our results suggest that clinicians need to raise their awarene...

A man who learns he has prostate cancer faces a difficult choice: whether to immediately treat the cancer despite potential side effects or wait and see if it's a slow-growing tumor that never needs treatment.

Men may soon have help making that decision.

Researchers from the United Kingdom report that they've created a urine test that can predict the aggressiveness of a pr...

A possible link between World Trade Center dust and prostate cancer in first responders has been found by researchers.

Exposure to dust at the New York City site after the Sept. 11, 2001, terrorist attacks triggered chronic inflammation in the responders' prostates, which may have contributed to their cancer, according to the Mount Sinai Health researchers.

They noted that i...

While men with early-stage prostate cancer can delay treatment, few follow guidelines for monitoring their condition, researchers report.

In fact, their study of nearly 350 men from North Carolina found that only 15% who chose what's known as active surveillance followed the recommended guidelines.

"Active surveillance has rigorous guidelines -- people need regular PSA t...

Cutting-edge prostate cancer drugs that help extend life in the toughest cases might also be useful in fighting less aggressive tumors, two new clinical trials suggest.

Two drugs that interfere with cancer's ability to use testosterone for fuel, apalutamide (Erleada) and enzalutamide (Xtandi), are already approved for use against more advanced prostate tumo...

Good news on a major killer: U.S. cancer deaths continued to fall between 1999 and 2016.

So finds the latest Annual Report to the Nation on the Status of Cancer, from a consortium of leading cancer organizations.

The report also found that the rate of new cancer cases fell among men from 2008 to 2015, after increasing from 1999 to 2008, and was stable in women from 1999 to ...

"Watchful waiting" is on the rise overall among U.S. men with low-risk prostate cancer, but black men remain less likely to opt for it, a new study finds.

For the study, researchers examined 2010-2015 data on more than 50,000 low-risk prostate cancer patients in the United States. The investigators found that black men were 16% less likely than other men to decide on watchful wai...

Some people with sleep apnea have an increased risk of cancer, and the odds may be higher for women than men, researchers say.

"Recent studies have shown that low blood oxygen levels during the night and disrupted sleep, which are both common in [obstructive sleep apnea], may play an important role in the biology of different types of cancers," said study leader Athanasia Pataka.

...

To treat, or not to treat: That remains one of the tough conundrums for men with prostate cancer and their doctors, because some tumors may be aggressive, while others may take decades to cause harm.

Now, new research suggests that tracking specific changes in the number of chromosomes inside prostate cancer cells might help solve the riddle.

Besides giving new insights into...

Men who take medicines for an enlarged prostate can have years-long delays in their diagnosis of prostate cancer and more advanced prostate cancer when they're diagnosed, a new study finds.

The reason? Drugs in this class -- such as Proscar (finasteride) and Avodart (dutasteride) -- can drive down blood levels of prostate-specific antigen (PSA). That's the blood marker doctors period...

When men with prostate cancer have to take drugs that block the testosterone fueling their tumors, they can suffer a host of side effects that include impotence, bone loss, heart trouble and obesity.

But new research uncovers yet another possible downside to the treatment: These men may be at greater risk for dementia.

For any type of dementia, th...

Good news for men: That blood pressure medication you're taking might be doing double duty, helping reduce your risk of developing prostate cancer, a new study shows.

Researchers found that a beta blocker called atenolol cut men's risk of intermediate-grade prostate cancer about in half, compared with men not taking a beta blocker.

It also appeared to significantly reduce th...

Treating men with low-risk prostate cancer with just one high dose of radiation may be safe and effective, British researchers report.

Therapy for prostate cancer typically involves low-dose radiation given over several days or weeks. Conversely, high-dose radiation is given once through a set of tiny tubes inserted directly into the tumor.

"For low-risk patients, a single ...

Rates of prostate cancer cases and deaths have declined or stabilized in many countries. And the United States had the largest recent decrease in disease incidence, a new study says.

"Previous studies have indicated significant variation in prostate cancer rates, due to factors including detection practices, availability of treatment, and genetic factors," said study author MaryBeth F...

Hormonal treatment can help control prostate cancer but may increase a man's risk of depression, a new study by Danish researchers suggests.

Male hormones, such as testosterone, are known to fuel the growth of prostate tumors. So doctors use drugs to reduce hormone production. But that can bring on tough side effects, such as incontinence or impotence.

The new study found ...

Will an aspirin a day keep prostate cancer at bay?

Not necessarily, according to new research.

Danish scientists say low-dose aspirin doesn't seem to reduce a man's risk of death from prostate cancer, but it may slow down the disease in some cases.

For patients with slow-growing, non-aggressive cancer, aspirin did appear to stop the cancer from progressing. A slig...

A new report from the American Cancer Society brings good news and bad news for black Americans.

The number of black lives lost to cancer is falling, the report finds, and at a faster rate than observed among whites. That's helping to close a decades-long "race gap" in cancer deaths between blacks and whites.

"Seeing the substantial progress made over the past several decade...

Many more American men are now saying no to surgery for low-risk prostate cancer, and choosing to monitor the disease instead, a new study finds.

Over just five years, researchers found, the number of men who opted for monitoring tripled -- from 14 percent of patients in 2010, to 42 percent in 2015.

The shift followed new guidelines advocating "active surveillance" as an op...

Finasteride, best known as the enlarged-prostate medicine Proscar, is a safe, effective way to reduce the risk of prostate cancer, according to long-term findings from the Prostate Cancer Prevention Trial (PCPT).

The trial was funded by the U.S. National Cancer Institute and enrolled nearly 19,000 men between 1993 and 1997.

Initially it found that finasteride -- a hormone-bl...

Over the past 25 years, the number of Americans who have died from cancer has dropped dramatically, though racial and economic disparities persist, a new study reveals.

Between 1991 and 2016, deaths from cancer dropped 27 percent. In real numbers, that's almost 2.6 million fewer cancer deaths, according to the American Cancer Society.

"The decline in deaths is largely driven...

Men with inflammatory bowel disease have a significantly greater risk of prostate cancer, a new study finds.

About 1 million men in the United States have inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis.

"These patients may need to be screened more carefully than a man without inflammatory bowel disease," said study lead author Dr. Shilajit ...