Results for search "Research &, Development".
Some HIV patients are naturally able to keep the virus fully in check without any medicinal help, a phenomenon that has intrigued scientists for decades.
New research appears to identify at least one reason why: an abnormally powerful version of an infection-fighting white blood cell called CD8+ T cell.
CD8+ T cell’s are a type of T cell, a normal feature in everyone’s immu...
Researchers have isolated for the first time a free-floating form of amyloid beta that appears to be a key driver of Alzheimer's disease.
Further, they argue that a newly approved Alzheimer's drug — lecanemab (Leqembi) — directly targets these small, complex chains of amyloid beta (A-beta) called fibrils. The U.S. Food and Drug Administration approved lecanemab in January.
The A...
Last year, gene researchers made news by announcing the completion of the first complete sequence of the human genome.
That effort has now been expanded, with researchers using that success as a springboard to create a comprehensive and sophisticated collection of genome sequences that more accurately captures human diversity.
The new “pangenome” includes the genome sequences of...
Artificial intelligence (AI) research and development should stop until its use and technology are properly regulated, an international group of doctors and public health experts said.
Certain types of AI pose an “existential threat to humanity,” the experts wrote in the May 9 issue of the journal
The United States needs to address a shortage of research monkeys by expanding breeding programs while also developing alternatives to monkey testing, an expert panel said in a report released Thursday.
The National Academies of Sciences, Engine...
Brain cancers are notoriously difficult to treat because most chemotherapy drugs can't breach the blood-brain barrier, a microscopic layer of cells that protect the brain from toxins.
But researchers now say they can temporarily open that barrier and get more chemo to brain tumors, using an experimental ultrasound device.
The technology led to a four- to sixfold increase in chemo dr...
Could an electronic chest “tattoo” -- wireless, lightweight and razor-thin -- upend heart monitoring and lower the odds of heart disease for folks who are at high-risk?
Just possibly.
The clear patch in question is not quite 4 by 5 inches in size, weighs less than an ounce, and is powered by a battery no bigger than a penny and just like a temporary tattoo sticker, it's designe...
Could a one-hour procedure that involves zapping a part of the intestines mean no more insulin for millions of folks with type 2 diabetes?
Maybe, according to a small study scheduled for presentation next week at the Digestive Disease Week meeting in Chicago.
The new minimally invasive procedure used controlled electrical pulses to change the lining of the first part of the small i...
When exercise studies are led by men, female participants are often in short supply.
While this underrepresentation of female research subjects has been documented in everything from clinical trials to cell cultures, a new study links researchers' gender and women's participation.
“Our findings provide direct evidence of the link between gender of authors and gender of research pa...
Researchers are reporting progress on the path to a "universal" flu vaccine -- one that would battle all strains of the virus and give the world a weapon against future flu pandemics.
In an early clinical trial, U.S. government scientists found that their experimental flu vaccine was able to coax recipients' immune systems to produce "cross-reactive" antibodies. That is, they made antibod...
An experimental blood test may be able to catch a dozen different types of cancer with a high degree of accuracy — including some that are particularly tricky to detect, a preliminary study suggests.
Researchers found that the blood test was usually on the money in detecting "signals" from 12 cancers. Importantly, the test was highly accurate in picking up early-stage cancer — which i...
New research in mice shows promise for a potential therapy for pancreatic cancer, which can be aggressive and hard to treat.
Researchers from Houston Methodist tested a device that, while smaller than a grain of rice, could deliver immunotherapy directly into a pancreatic tum...
A new national Alzheimer's disease and dementia database could be a game changer for research on the memory-robbing condition that now affects more than 6 million Americans.
Planning has begun at the National Institute on Aging (NIA) to fund the data platform. A $300 million grant for the six-ye...
An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials.
Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds at all after nine months, versus just 5% of people treated with drugs that enhance clotting, according to a trial published onlin...
Lawyer, entrepreneur and avid athlete Mark Clements participated in the 2005 St. George Marathon in Utah, but ongoing stomach pains made finishing the event a struggle.
“He was having some stomach pain,” recalled his sister Stacie Lindsey. “My dad had had ulcers, and so he thought that he had ulcers.”
After finishing the marathon, Clements, then 38, went straight in to see h...
An injection that relieves low back pain by helping damaged spinal discs regenerate appears to have sustained benefits, new clinical trial data show.
Most patients who received an injection of VIA Disc received back pain relief that lasted at least three years, said lead researcher Dr. D...
Swedish scientists say they have grown electrodes in living tissue, paving the way for formation of fully integrated electronic circuits in living organisms.
The development, which blurs the lines between biology and technology, could one day lead to therapies for neurological disorders.
“For several decades, we have tried to create electronics that mimic biology. Now we let biolo...
A single injection of an experimental biologic drug may cut in half your risk of hospitalization from COVID-19 infection, new clinical trial results show.
Pegylated lambda interferon (PEG-lambda) proved effective against all COVID-19 variants encountered in this international study, including Omicron, according to findings reported Feb. 9 in the
An artificial pancreas has long been considered the holy grail for people with type 1 diabetes, and new research suggests a more convenient version of this technology may help the millions of people living with type 2 diabetes.
Type 2 is the more c...
Few good treatment options exist for the millions of women dealing with the intense pain caused by endometriosis, but researchers say a new "cellular atlas" could help.
A team at Cedars-Sinai Medical Center in Los Angeles has developed a detailed molecular profile of endometriosis using data from 400,000 patient cells.
“Endometriosis has been an understudied disease in part beca...
A new study on pigs shows promise for repairing penile injuries in humans.
Scientists in China developed a synthetic tissue that reportedly repairs injuries and restores normal erectile function in pigs. This artificial tunica albuginea (ATA) mimics a fibrous sheath of tissue that is necessary to maintain erections.
"We noticed that this is an area that has received little attention...
As the United States moves towards a world in which electric vehicles (EVs) have fully replaced fossil fuel-driven engines, can Americans look forward to reliably cleaner air and better health?
Absolutely, a new study predicts.
By 2050, researchers say, th...
One might expect identical twins to have the same health outcomes.
But it's not just genetics that makes a notable difference in their weight and in how their genes behave, according to a new study. Exercise can alter genetic markers of metabolic disease -- any of the diseases or disorders that disrupt norma...
It's thought that for an HIV vaccine to be widely effective, it will have to spur the body to make special antibodies that can neutralize a broad range of HIV strains. Now scientists say they have taken an essential step in that direction.
In an early study, researchers found that an experimental HIV va...
The experimental Alzheimer's drug lecanemab slowed thinking declines among patients suffering the early stages of the disease in a new study, but safety concerns about brain swelling and brain bleeds remain.
In the eagerly awaited trial findings, published Tuesday in the New England...
The breast cancer of author and poet Stephanie Gangi has receded and advanced in wearying waves for two decades now.
First diagnosed and treated in 1999, Gangi's cancer spread to the bone of her sternum in 2014. In 2021, a tumor the size of an orange appeared on her adrenal gland.
“I could not possibly tell you the number of treatments I've been through,” said Gangi, 66, of New ...
A new malaria antibody treatment may keep more people free of the sometimes deadly disease for up to six months in regions where infection rates are high.
Instead of requiring the immune system to make enough antibodies, this experimental drug provides those who receive it with a large amount of lab-made antibodies. It requires an infusion via IV, but a shot version of the drug is in ear...
In what could be an advance against hair loss, researchers say they've successfully grown hair follicles in culture in the lab.
The Japanese research team created a system that produces fully mature hair follicles — the tube-like structure in which the root and strand of a hair grow — as well as hair as l...
The U.S. National Institutes of Health is investigating COVID experiments at Boston University that have sparked a media firestorm, with some news outlets alleging that scientists created a "killer" strain of the coronavirus as part of their research.
Boston University is refuting those news accounts, calling them a "false and inaccurate" interpretation of its research.
"They've sen...
Scientists have taught a brain cell culture living in a laboratory dish to play the vintage table-tennis video game Pong.
It's the first demonstration that a collection of lab-grown brain cells can be taught to perform goal-directed tasks, the Australian researchers report.
They call the culture...
Human brain tissue has been successfully transplanted into the brains of rats using a cutting-edge experimental procedure, say researchers. They envision the achievement as a promising new frontier in medical research.
Groups of living human nerve cells have become integrated into the brains of laboratory rats, creating hybrid brain circuits that can be activated through input from the ra...
A leading medical journal, the British Journal of Sports Medicine, has retracted nine more articles written by its former editor-in-chief and applied “expressions of concern” on 38 additional articles on which he is the sole author that were published in BMJ journals.
This is the latest development in the investigation, which concerns possible plagiarism and misrep...
Swedish scientist Svante Paabo received the Nobel Prize in medicine on Monday.
The 67-year-old researcher made important discoveries about human evolution and the immune system while comparing modern humans and early hominins. After developing new techniques, Paabo and his team made it possible to compa...
President Joe Biden made a renewed push for his cancer moonshot initiative on Monday.
Speaking at the famed John F. Kennedy Presidential Library and Museum in Boston, Biden likened JFK's space race to his own effort to slash cancer rates by 50% in the next 25 years.
“He established a national purpose that cou...
A single blood test that can screen for more than 50 cancers seems to work fairly well in the real world, a preliminary study reveals.
Researchers found that of over 6,600 apparently healthy people aged 50 and older, the blood test detected a possible cancer "signal" in roughly 1%. When those individuals had more extensive testing, cancer was confirmed in 38%.
An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain.
Affecting as many as 1.5 million people in the United States, lupus is an autoimmune disease in which the body's immune system misfires against its own joints, skin, brain, lungs, kidneys and blood vesse...
In a finding that proves convenience is key when it comes to sticking to a medication regimen, new research shows that combining three heart drugs into one "polypill" slashes the risk of dying from a second heart attack by 33%.
"The results of the SECURE study show that for the first time that the polypill, wh...
Using only mouse stem cells, British researchers report they have created synthetic embryos that form a brain, a beating heart and other organs.
The stem cells organized themselves until they developed beating hearts and the foundations of the brain and yolk sacs where the embryo...
An experimental antibody therapy for multiple sclerosis can cut symptom flare-ups by half, versus a standard treatment, a new clinical trial has found.
The drug, called ublituximab, beat a standard oral medication for
A person's unrelated lookalike, commonly known as a doppelganger, may actually share genes that affect not only how they appear, but also their behavior.
In a new study, scientists did DNA analysis on 32 sets of virtual twins — people with strong facial similarities — and found they possessed similar genetic variants.
“Our study provides a rare insight into human likeness by...
If you think hallucinogens like LSD are a thing of the past, think again.
New research estimates that the use of mind-altering LSD rose from less than 1% in 2002 to 4% in 2019 among people aged 18 to 25. And, overall, 5.5 million Americans used some kind of hallucinogen in 2019.
"According to our results, hallucin...
Strike up the band!
A new study finds that the aerosols produced by wind instruments like trombones and flutes are no more concerning than those given off during normal speech and breathing.
For the study, University of Pennsylvania researchers worked with the Philadelphia Orchestra to better understand how much
Minutes after a heartbeat stops, a massive series of disastrous events triggered by lack of blood flow begins to destroy a body's cells and organs.
This chain of events had been thought to be inevitable and irreversible. Now, a new animal study shows that
The future of ultrasound imaging could be a sticker affixed to the skin that can transmit images continuously for 48 hours.
Researchers at Massachusetts Institute of Technology (MIT) have created a postage stamp-sized device that creates live, high-resolution images. They reported on their progress this week.
...
A drug in development as a cancer therapy may also help the body regenerate damaged nerves after spinal injuries, new research suggests.
Scientists at the University of Birmingham in the United Kingdom report that they used cell and animal models to show that the drug, dubbed
Hinting at a future alternative to opioid painkillers, scientists have developed a tiny implant designed to ease post-surgery pain and then dissolve once the job is done.
So far, the research has been limited to lab animals, and it will be several years before the technology could be ready for human testing....
When breast cancer patients sleep, tumor cells may "awaken" and spread through the bloodstream, a surprising study out of Switzerland reveals.
Circulating cancer cells that later form new growths (metastases) do not arise continuously as previously assumed, according to researchers at ETH Zurich, the University Hospital Basel and the University of Basel.
"When the affected person is...
An experimental Alzheimer's drug called crenezumab did not prevent or slow mental decline in patients with a genetic mutation that greatly raises the risk of developing the disease, the results of a decade-long clinical trial show.
The mutation seen in the few hundred study participants from an extended famil...
Cancer clinical trials in the United States appear to be rebounding after a significant slowdown during the pandemic, researchers say.
For the study, the investigators analyzed data from the Dana-Farber Cancer Institute in Boston and the Tisch Cancer Institute at Mount Sinai Medical School in New Y...
An experimental drug for the neurological disorder ALS was approved in Canada on Monday, but an ongoing evaluation of the treatment by the U.S. Food and Drug Administration has raised questions about its effectiveness.
A condition of Hea...